Schauspieler
Sarah Paulson (Marcia Clark), John Travolta (Robert Shapiro), Sterling K. Brown (Christopher Darden), Kenneth Choi (Judge Lance Ito), Christian Clemenson (Bill Hodgman), Cuba Gooding Jr. (O.J. Simpson), Bruce Greenwood (Gil Garcetti), Nathan Lane (F. Lee Bailey), David Schwimmer (Robert Kardashian), Courtney B. Vance (Johnnie Cochran), Lady Gaga, Dale Godboldo (Carl E. Douglas), Ariel D. King (Arnelle Simpson), Tye White (Jason Simpson), Angel Parker (Shawn Chapman), Jessica Blair Herman (Kim Goldman), Leonard Roberts (Dennis Schatzman), Joseph Siravo (Fred Goldman), Susan Beaubian (Armanda Cooley), P.L. Brown (Easter Island), Roslyn Gentle (The Demon), Jeris Poindexter (Juror), Jenna Willis (Tanya Brown), Chris Conner (Jeffrey Toobin), Rob Morrow (Barry Scheck), Robert Morse (Dominick Dunne), Keesha Sharp (Dale Cochran), Kelsey Griswold (Dominique Brown), Mary Anne McGarry (Juditha Brown), Chris Bauer (Detective Tom Lange), Jordana Brewster (Denise Brown), Garrett M. Brown (Lou Brown), Annaleigh Ashford (Paula Jones), Darren Criss (Andrew Cunanan), Beanie Feldstein (Monica Lewinsky), Clive Owen (William Jefferson Clinton), Javier Garcon (Paparazzi; Camera Man), Edgar Ramírez (Gianni Versace), Chuck Ashworth (Bailiff), Ricky Martin (Antonio D'Amico), Penélope Cruz (Donatella Versace), Michael McGrady (Detective Phillip Van Atter), Steven Pasquale (Detective Mark Fuhrman), Christopher Boyer (Juror), Cocoa Brown (Queen Bee), Diana Daves (Golden Girl), Virginia Louise Smith (Francine Florio-Bunten), Noree Victoria (En Vogue), Cassius M. Willis (Juror), China Shavers (Shirley Simpson), Finn Wittrock (Jeffrey Trail), Cody Fern (David Madson), Joanna Adler (Mary Ann Cunanan), Evan Handler (Alan Dershowitz), Cheryl Ladd (Linell Shapiro), Larry King (Larry King), Malcolm-Jamal Warner (Al Cowlings), Isabella Balbi (Kourtney Kardashian), Morgan Bastin (Khloe Kardashian), Nicolas Bechtel (Rob Kardashian), Michael Graham (Deputy OJ), Veronica Galvez (Kim Kardashian), Valeri Ross (Eunice 'Mama' Simpson), Peggy Blow (Miriam)
Regie
Ryan Murphy, Anthony Hemingway, Gwyneth Horder-Payton, Daniel Minahan, John Singleton, Matt Bomer, Nelson Cragg, Richard Shepard
Drehbuch
Jeffrey Toobin, Scott Alexander, Larry Karaszewski, Maureen Orth, Tom Rob Smith, Sarah Burgess, D.V. DeVincentis, Joe Robert Cole, Maya Forbes, Wallace Wolodarsky, Maggie Cohn
